Best Vitamins & Supplements for Hormonal Acne - Dr. Jolene ... Jun 24, 2022 · The best vitamins for acne are vitamin A, vitamin C, vitamin E, and a B complex. You can find many of these nutrients in food, but taking supplements can ensure you're getting enough. What Supplement Is Best for Hormonal Acne? No single supplement is the best for hormonal acne because each person is different.